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. 2003 May 15;100(11):6640–6645. doi: 10.1073/pnas.1232239100

Table 3. Interaction between CAF-I or RCAF defects and checkpoint defects.

Wild type
cac1Δ
asf1Δ
Relevant genotype Strain no. Mutation rate (Canr 5-FOAr) Strain no. Mutation rate (Canr 5-FOAr) Strain no. Mutation rate (Canr 5-FOAr)
Wild type 3615 3.5 × 10-10 (1)* 4753 1.2 × 10-7 (343) 4755 2.5 × 10-8 (71)
rad9Δ 3719 2.0 × 10-9 (6)* 4757 4.0 × 10-7 (1,142) 4759 1.0 × 10-7 (285)
rad24Δ 3723 4.0 × 10-9 (11)* 4761 4.8 × 10-7 (1,371) 4763 2.0 × 10-7 (571)
sgs1Δ 3814 7.7 × 10-9 (22)† 4765 6.3 × 10-7 (1,800) 4767 9.7 × 10-8 (278)
rfc5-1 3727 6.6 × 10-8 (189)* 4769 1.3 × 10-7 (371) 4771 8.6 × 10-7 (2,457)
dpb11-1 4538 9.0 × 10-8 (257)* 4773 1.2 × 10-7 (342) 4775 2.3 × 10-7 (657)
mec1Δ sml1Δ‡ 3735 6.8 × 10-8 (194)* 4789 5.2 × 10-7 (1,486) 4791 1.7 × 10-7 (486)
dun1Δ 3739 7.3 × 10-8 (208)* 4801 5.6 × 10-7 (1,600) 4803 6.9 × 10-8 (197)
chk1Δ 3745 1.3 × 10-8 (37)* 4807 8.0 × 10-7 (2,285) 4809 6.9 × 10-8 (197)

The numbers in parentheses are the fold increases in rate relative to that of the wild-type strain.

*

Data are from Myung et al. (55).

†

Data are from Myung et al. (57).

‡

GCR rate of the sml1 strain was 3.1 × 10-10 (1).