Figure 2.
Effect of scopolamine (0.1, 0.3 or 1 mg kg−1, i.p.) pretreatment on stretching induced by Ro 04-6790. Rats were pretreated with scopolamine and 30 min later with either Ro 04-6790 (30 mg kg−1, i.p.) or saline and placed in observation cages in groups of four. After a further 30 min the animals were observed for 1 h and the number of stretches recorded. Results are expressed as the total number of stretches (mean±s.e.mean, n=8) observed in 1 h. *P<0.05 compared to saline/saline treated rats and +P<0.05 compared to saline/Ro 04-6790 (30 mg kg−1, i.p.) treated rats (Mann-Whitney U-test following a Kruskal Wallis ANOVA, H(5,6)=20.5, P=0.001).