Table 2.
Terlipressin (TP) treatment and outcome
| Patient | Time from PICU admission to TP therapy (hours) | Time of maintenance of TP therapy (hours) | Adverse effectsa | PICU length of stay (days) | Survival of episode | Cause of death | Sequela |
| 1 | 40 | 48 | No | 49 | Yes | Minor amputation (one right hand finger) | |
| 2 | 4 | 32 | Ischemia (limited to toes) | 7 | Yes | No | |
| 3 | 12 | 65 | No | 51 | No | Refractory shock | |
| 4 | 6 | 3 | Severe limbs and cutaneous ischemia, hyperkalemia | 6 | No | Ventricular fibrillation | |
| 5 | 24 | 24 | Limbs and cutaneous ischemia | 22 | Yes | Major amputation: lower limbs (below knees) and both hands | |
| 6 | 72 | 102 | No | 49 | Yes | Minor amputation (one hand finger) | |
| 7 | 26 | 8 | Severe limbs ischemia, cutaneous ischemia, hyperbilirubinemia | 14 | No | Withdraw of therapy | |
| 8 | 48 | 20 | Rabdomyolisis? | 22 | Yes | No | |
| 9 | 4 | 5 | Oliguria | 9 | Yes | Partial anopsy, dismetry | |
| 10 | 32 | 96 | Cutaneous and intestinal ischemia | 6 | No | Withdraw of therapy | |
| 11 | 168 | 52 | Limb and cutaneous ischemia, oliguria | 8 | No | Multiorgan failure | |
| 12 | 14 | 7 | No | 1 | No | Arrhythmia | |
| 13 | 60 | 8 | No | 3 | No | Ventricular fibrillation | |
| 14 | 20 | 20 | No | 1 | No | Refractory shock | |
| 15 | 5 | 18 | Limbs ischemia, rabdomyolisis | 2 | No | Refractory shock | |
| 16 | 48 | 72 | Limbs and cutaneous ischemia | 14 | Yes |
PICU, pediatric intensive care unit. aBased in the opinion of the responsible physician