FIG. 5.
Comparison of the V1 and V2 regions (A), V3 loop analog (B), and GDPE motif and V4 region (C) in sequential plasma samples from Rh445 (top) and Rh444, Rh455, and Rh460 (normal progressors). The amino acid sequences derived from plasma viral RNA are compared to that of SIVsmE543-3. Amino acid substitutions are indicated, identity is indicated by a dash, and an asterisk indicates in-frame deletions. Sequential samples from 2, 8, and 17 weeks postinfection of the RP, H445, are at the top portion of each panel. Env clones from 52 weeks postinoculation from the progressors, 444, 455, and 460, are in the bottom portion of each panel. The time of plasma sample collection is indicated in terms of weeks postinoculation. The number of clones showing the indicated sequence is shown. The V1 to V5 regions and the GDPE motif are indicated above the sequence.