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Summary of permissive and restrictive 3T3 cell subsets. Cell lines permissive for (shaded) or restrictive to (white) MV replication were derived from NIH 3T3 murine fibroblasts by stable transfection with plasmids expressing human CD4. Additional cell lines that retained the parental phenotype were generated following transfection of permissive 3T3.CD4 cells with the human chemokine receptors CCR5 or CXCR4 and transfection of restrictive 3T3.CD4.neo cells with CX3CR1.
