Table 1.
Baseline patient characteristics
| Patient | Baseline CD4, cells per mm3 | Baseline plasma HIV RNA, copies per ml | Pre-HAART plasma RNA, copies per ml | Mos. on nonsuppressive 3TC regimen | Years on HAART | Pre-HAART regimen | HAART regimen | Blip on HAART |
|---|---|---|---|---|---|---|---|---|
| M1 | 312 | 57,619 | 46,946 | 10 | 4.5 | ZDV/3TC | ZDV/3TC/IDV | Yes |
| M2 | 144 | 43,091 | 12,920 | 10 | 4.5 | ZDV/3TC | ZDV/3TC/IDV | No |
| M3 | 63 | 22,604 | 6,444 | 12 | 4 | ZDV/3TC | ZDV/3TC/IDV | No |
| S1 | 385 | 168,486 | 25,027 | 7 | 3 | ZDV/3TC | ddI/D4T/RIT | No |
| S2 | 588 | 268,765 | 27,317 | 7 | 2.5 | ZDV/3TC | ddI/3TC/IDV | No |
| S3 | 595 | 42,793 | 2,202 | 9 | 2.5 | ZDV/3TC | ddI/D4T/NFV | No |
| D1 | 243* | NA | 118,733 | 9 | 4 | ZDV/3TC/d4T | EFV/IDV | No |
| D2 | 349* | NA | 68,603 | 15 | 3.5 | ZDV/3TC/d4T | EFV/IDV | No |
| D3 | 422* | NA | 21,419 | 10 | 4 | ZDV/3TC/ddC | EFV/IDV | No |
NA, not available; ZDV, zidovudine; 3TC, lamivudine; IDV, indinavir; ddI, didanosine; d4T, stavudine; NFV, nelfinavir; RIT, ritonavir; EFV, efavirenz.
*
Pre-HAART CD4.