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Combined CIP4 and ubiquitin immunofluorescence in the superior frontal cortex, layer 6, in HD patients. Combined immunofluorescence for CIP4 (red) (A) and ubiquitin (green) (B) immunoreactivities within the same tissue specimen from the superior frontal cortex of a HD patient grade 3 shows colocalization of ubiquitin-positive inclusions and CIP4 immunostaining in the merged figure (yellow) (C).
