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Validated Cessation Treatments
| First-Line Therapies | Availability | Efficacy (Odds Ratio) |
|---|---|---|
| Bupropion | Rx | 2.1 |
| Nicotine gum | OTC | 1.5 |
| Nicotine patch | OTC | 1.9 |
| Nicotine inhaler | Rx | 2.5 |
| Nicotine lozenge | OTC | 1.7 |
| Behavior therapy | Group, individual, or telephone | 1.5 |
| Supportive therapy | Group, individual, or telephone | 1.5 |
| Second-line therapies | ||
| Nicotine nasal spray | Rx | 2.7 |
| Clonidine | Rx | 2.1 |
| Nortriptyline | Rx | 2.7 |
Rx, prescription; OTC, over the counter.
