Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Depletion of p53 by RNAi prolongs cell survival following cisplatin treatment. (A and B) p53 siRNA or control siRNA was transfected into WT Bcl2-expressing H7 cells using Lipofectamine 2000. Cells were treated with cisplatin (10 μM) for 72 h, and the levels of p53 expression were analyzed by Western blotting using a p53 antibody. Cell viability was assessed as described in the legend for Fig. 1C. Data represent the mean ± standard deviation of three separate experiments.
