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Clinical EAE course in male and female B6, B6.YA, and B6.Yaa progeny elicited by using the single MOG35–55 plus CFA plus PTX induction protocol. As summarized in Table 3, no significant difference in the incidence of clinical disease was seen among the progeny of consomic lines; however, significant differences in the mean cumulative disease scores, mean peak scores, mean days affected, and mean severity indices were observed.
