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. 2006 Mar;172(3):1783–1797. doi: 10.1534/genetics.104.039313

TABLE 2.

Mean effects for each multilocus genotype in simulated additive and epistatic QTL systems

QTL system Genotype Genetic effect (arbitrary units)
Single aa 0
aA 5
AA 10
Epistatic aabb 0
aAbb 0
AAbb 0
aaBb 0
aABb 5
AABb 10
aaBB 0
aABB 10
AABB 20

In nonepistatic simulations, the genetic effects of background and foreground QTL follow the additive scheme. In epistatic simulations, background QTL act additively but the foreground QTL and the unlinked masking QTL act according to the epistatic scheme. Note that, although listed, heterozygous genotypes are extremely rare in inbred RIAIL, RIHS, and CC populations. For this reason, we excluded dominance effects from either model.