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Fig. 6. Lack of a visceral phenotype and a short systemic half-life of transgene encoded proteins. (A) Pericardial lymphatic vessels of a K14-VEGF-C156S × VEGFR-3+/LacZ compound heterozygous and a VEGFR-3+/LacZ mouse were analysed by β-galactoside staining. (B) Relative amounts of VEGF-C, VEGF-D and VEGF in mouse circulation as a function of time after an intravenous injection of recombinant protein. The dashed line denotes 1/2 of the maximum growth factor concentration just after injection.
