Table 1.
Clinical and neuroanatomical features of reported parakinesia brachialis oscitans cases. Cases are ordered chronologically by year of publication. Full case-level data are given in Supplementary Table 3. CADASIL, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; ICA, internal carotid artery; MCA, middle cerebral artery; NR, not reported; PBO, parakinesia brachialis oscitans; PCA, posterior cerebral artery.
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| # | AUTHOR (YEAR) | AGE/SEX | LESION/DIAGNOSIS | SYMPTOM LATERALITY | LIMB(S) AFFECTED | TIME TO ONSET | PBO OUTCOME |
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| 1 | Blin et al. (1994) | 62/M | Left posterior limb of internal capsule infarct | Right | Upper & Lower | A few days | Persisted at 6 weeks |
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| 2 | Töpper et al. (2003) | 62/M | Right PCA and MCA territory infarction | Left | Upper | NR | NR |
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| 3 | Töpper et al. (2003) | 43/M | Basilar artery thrombosis with right pontine infarct | Left | Upper | 4 days | NR |
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| 4 | Töpper et al. (2003) | 51/M | Hypertensive left thalamic hemorrhage extending into the internal capsule | Right | Upper | 2 weeks | NR |
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| 5 | Walusinski et al. (2010) | 49/F | Right internal capsule infarct in the setting of CADASIL (NOTCH3 mutation) | Left | Upper | 2 days | Resolved at 2 weeks with motor recovery |
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| 6 | Walusinski et al. (2010) | 73/M | Left internal capsule lacunar infarct | Right | Upper | At presentation | Resolved at 1 week with partial recovery and residual ataxia |
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| 7 | Walusinski et al. (2010) | 71/M | Right centrum semiovale and lenticular nucleus infarct | Left | Upper | At presentation | Persisted at 3 years |
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| 8 | Walusinski et al. (2010) | 53/M | Right caudate and centrum semiovale infarct in the setting of factor V Leiden | Left | Upper | At presentation | Persisted at 1 year |
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| 9 | Walusinski et al. (2010) | 75/M | Left internal capsule and lenticular nucleus infarct | Right | Upper | At presentation | NR |
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| 10 | Walusinski et al. (2010) | 35/F | Left total MCA territory infarct in the setting of ICA dissection and fibromuscular dysplasia | Right | Upper | At presentation | NR |
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| 11 | de Lima et al. (2012) | 63/M | Right cortical and subcortical frontoparietal infarct | Left | Upper | 2 months | NR |
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| 12 | Jung et al. (2012) | 59/M | Right precentral gyrus and frontal subcortical infarct | Left | Upper | 1 day | Resolved, timing NR, by 5-year follow-up |
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| 13 | Zorzetto et al. (2013) | 60/M | Left MCA territory infarct | Right | Upper | During thrombolysis | Resolved at 24 hours |
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| 14 | Wu et al. (2013) | 52/M | Right putaminal hemorrhage extending into the internal capsule | Left | Upper | 4 months | Persisted, increasing in frequency and intensity |
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| 15 | Farah et al. (2015) | 51/M | Left fronto-parieto-temporal infarct | Right | Upper | 2 days | Resolved at 12 hours |
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| 16 | Kang and Dhand (2015) | 63/M | Left cortical and subcortical infarct in the MCA territory | Right | Upper | NR | Resolved at 2 weeks with partial recovery of arm strength |
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| 17 | Koo and Wang (2016) | 57/F | Right internal capsule infarct | Left | Upper | A few days | NR |
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| 18 | Nascimento Alves et al. (2018) | 59/M | Left lenticular nucleus, internal capsule, caudate and corona radiata infarct | Right | Upper | At presentation | NR |
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| 19 | Aaron and Al Hashmi (2019) | 53/F | Right pontine and upper medullary infarct | Left | Upper | 2 days | Resolved at 3 days |
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| 20 | Gadelha et al. (2019) | 65/F | Right MCA territory infarct with M1 occlusion | Left | Upper | During thrombolysis | NR |
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| 21 | Chowdhury et al. (2022) | 59/M | Left frontal cortex and basal ganglia infarct with hemorrhagic transformation | Right | Upper | 2 weeks | Persisted at 1 year with reduced amplitude |
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| 22 | Lim and Neo (2022) | 65/M | Right corona radiata and internal capsule infarct | Left | Upper | 17.5 hours | Resolved, timing NR, with recovery of motor power |
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| 23 | Salavisa et al. (2023) | 35/M | Right centrum semiovale demyelinating lesion; multiple sclerosis | Left | Upper | 2 weeks | Improved, then re-emerged with neurological worsening |
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| 24 | Zobiri et al. (2023) | 71/F | Internal capsule and lenticular nucleus infarct, right MCA territory | Left | Upper | NR | NR |
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| 25 | Tsai et al. (2024) | 31/M | Right deep subcortical white matter tumefactive demyelinating lesion | Left | Upper | At presentation | NR |
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| 26 | Alvarez and Alvarez (2025) | 76/M | Right frontal cortical-subcortical intracerebral hemorrhage | Left | Upper | NR | NR |
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| 27 | Orozco-Puga et al. (2026) | 20/F | Right internal capsule infarct in the setting of ICA dissection | Left | Upper | 1 week | NR |
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| 28 | Orozco-Puga et al. (2026) | 45/F | Left pontine infarct with hemorrhagic transformation | Right | Upper | 4 days | NR |
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| 29 | Orozco-Puga et al. (2026) | 49/F | Right frontal subcortical white matter infarct | Left | Upper | 2 weeks | NR |
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| 30 | AlJaafari and Shariff (2026) | 57/M | Left pontine infarct with basilar atherosclerosis | Right | Upper & Lower | 1 week | Resolved by 3 months |
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| 31 | Alcalá-Torres (2026) | 76/F | Right lenticular nucleus and internal capsule infarct | Left | Upper | 1 month | Resolved at 5 months |
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