Table 1.
Comparison of data between normal coronary artery and coronary artery disease groups
| Parameter | NCA (n = 60) |
CAD (n = 116) |
P value |
|---|---|---|---|
| Age, years | 58.6 ± 6.8 | 61.47 ± 8.6 | 0.032 |
| Gender (Female), n % | 29 (48.3) | 60 (51.7) | 0.670 |
| Height (cm) | 165.7 ± 6.3 | 164.8 ± 7.9 | 0.392 |
| Weight (kg) | 73.9 ± 7.8 | 75.2 ± 10.7 | 0.370 |
| BMI (kg/m2) | 26.9 ± 2.1 | 27.3 ± 2.9 | 0.224 |
| Hypertension, n (%) | 12 (20.0) | 71 (61.2) | < 0.001 |
| Diabetes mellitus, n (%) | 3 (5.0) | 68 (58.6) | < 0.001 |
| Family history of CAD, n (%) | 26 (43.3) | 69 (59.5) | 0.042 |
| Neutrophils (x109/L) | 4.7 ± 1.9 | 5.6 ± 1.99 | 0.004 |
| Lymphocytes (x109/L) | 2.3±0.65 | 2.2±0.81 | 0.502 |
| Hemoglobin (g/dL) | 14.0 ± 2.0 | 13.72 ± 1.78 | 0.269 |
| Platelets (x109/L) | 269.50 (225.0-313.25) | 240 (218.0-297.5) | 0.079 |
| Urea (mg/dL) | 30 (26–36) | 36 (28–40) | 0.011 |
| Creatinine (mg/dL) | 0.85 ± 0.22 | 0.87 ± 0.21 | 0.541 |
| Total cholesterol (mg/dL) | 184.6 ± 34.6 | 184.3 ± 42.0 | 0.959 |
| LDL (mg/dL) | 106.5 ± 28.8 | 107.2 ± 36.1 | 0.911 |
| HDL (mg/dL) | 43 (39.25-50.0) | 42 (36–50) | 0.513 |
| Triglycerides (mg/dL) | 140 (102.25–171.50) | 149 (106.5–218.0) | 0.224 |
| TGF-β (ng/mL) |
153.0 (148.25–156.00) |
132.6 (106.4-213.7) |
0.299 |
| PDGF-BB (ng/L) | 48.49 ± 9.59 | 50.1 ± 13.68 | 0.360 |
Values in bold indicate statistically significant differences between groups (p < 0.05)
NCA Normal coronary artery (Symptomatic control group), CAD Coronary artery disease, ACS Acute coronary syndrome, BMI Body mass index, TGF-β Transforming growth factor-beta, PDGF-BB Platelet-derived growth factor-BB, LDL Low-density lipoprotein, HDL High-density lipoprotein