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. 2026 Jul 1;6:549. doi: 10.1038/s43856-026-01744-x

Table 3.

Sleep characteristics across nights in TES15 kHz-TI1 Hz

Baseline night First night Last night Test statistic (X2 or F) p-value
Total sleep-wake period (hr) 8.06 ± 0.99 8.25 ± 0.85 8.12 ± 0.78 (X2) 0.88 0.646
Total sleep time (hr) 6.70 ± 0.83 7.04 ± 0.69 6.92 ± 0.79 (X2) 6.12 0.047†
Sleep onset latency (min) 22.97 ± 11.89 23.44 ± 13.38 21.50 ± 15.39 (X2) 2.51 0.285
REM latency (hr) 1.86 ± 0.70 2.06 ± 0.76 1.93 ± 0.77 (X2) 3.50 0.174
Sleep efficiency (%) 83.62 ± 8.89 85.65 ± 6.65 85.33 ± 7.27 (X2) 1.12 0.570
Number of arousals 57 ± 26 69 ± 34 64 ± 31 (X2) 1.24 0.538
Arousal index (arousals/hr) 8.54 ± 3.95 9.80 ± 4.60 9.42 ± 5.12 (X2) 0.88 0.646
Number of awakenings 21 ± 7 21 ± 8 20 ± 8 (X2) 1.76 0.414
Wake after sleep onset (min) 58.19 ± 47.17 48.56 ± 36.60 50.13 ± 36.78 (X2) 2.13 0.345
Stage N1 (%) 4.07 ± 1.85 3.96 ± 2.94 4.07 ± 3.71 (X2) 0.38 0.829
Stage N2 (%) 61.49 ± 9.83 61.88 ± 5.76 60.03 ± 5.65 (X2) 0.38 0.829
Stage N3 (%) 13.75 ± 6.40 13.50 ± 6.35 12.62 ± 6.31 (X2) 0.88 0.646
Stage REM (%) 20.70 ± 5.73 20.66 ± 2.91 23.28 ± 3.79 (X2) 1.62 0.444
Whole-night SWA (dB/Hz) 12.34 ± 2.71 12.12 ± 2.66 12.21 ± 2.69 (F) 1.16 0.327
First 4 hr SWA (dB/Hz) 12.54 ± 2.69 12.37 ± 2.75 12.45 ± 2.90 (F) 0.50 0.611

Across baseline, first, and last nights, TES15 kHz-TI1 Hz (N = 16) participants show no significant differences in any sleep characteristics after correction for multiple comparisons (Friedman test or one-way repeated measures ANOVA, Benjamini–Yekutieli procedure to correct for multiple comparisons). Mean ± standard deviation. Unadjusted p-values shown; when corrected for multiple comparisons, all adjusted p-values were > 0.999.

REM rapid eye movement, SWA slow wave activity.

†Total sleep time is not significant after correction for multiple comparisons (X2 = 6.12, unadjusted p = 0.047, adjusted p > 0.999).