Table 4.
Enriched Gene Ontology terms for 96 orthologous C. elegance genes comprising significantly differentiated H. contortous SNPs in the comparison between farm populations D and G
| GO terma | Term name | Term identity | Adjusted p-value | Term sizeb | Query sizec | Intersection sized | Effective domain sizee | Intersectionsf | Gene with HIGH/MODERATE impact SNPsg |
|---|---|---|---|---|---|---|---|---|---|
| GO:BP | nervous system development | GO:0007399 | 0.0199 | 434 | 72 | 12 | 10936 | FKH-9, MIG-2, SYG-1, SYD-2, CEH-40, DPFF-1, UNC-3, SAD-1, EOR-2, IMPT-1, MEK-1, UNC-6 | IMPT-1, SYD-2, SYG-1 |
| GO:CC | intracellular anatomical structure | GO:0005622 | 0.0149 | 6933 | 85 | 63 | 12900 | B0563.7, NSTP-10, FKH-9, GEI-15, BPL-1, MDT-6, EPG-7, GCY-35, QUI-1, MIG-2, T04G9.4, UGGT-1, Y57E12AL.6, SYD-2, DYC-1, SGK-1, RBC-1, NSTP-2, ASNS-2, CEH-40, HECD-1, MIGA-1, MTM-5, F26A10.2, TWNK-1, SIPA-1, PTR-14, HDA-11, EFL-2, DRH-1, DPFF-1, PKC-2, C25H3.15, ODD-2, T25B9.1, SGCA-1, UNC-3, GRK-1, AJM-1, F13E6.2, EOR-2, DHS-29, BED-3, Y57G11C.33, C24D10.6, UNC-82, DPF-5, GTA-1, COX-18, DISL-2, IMPT-1, MASK-1, NFU-1, MCM-2, ZK287.1, MEK-1, NHR-32, MBK-1, RRF-3, SEL-7, UNC-6, UNK-1, HOSL-1 | DISL-2, DRH-1, GEI-15, HECD-1, IMPT-1, MASK-1, MCM-2, MTM-5, NHR-32, PTR-14, QUI-1, RBC-1, RRF-3, SGCA-1, SYD-2, UNC-82 |
aMain category of gene ontology terms; Biological Process (GO:BP), and Cellular Component (GO:CC)
bNumber of background genes annotated to this term
cNumber of genes in our input list used for enrichment
dCount of our input genes that are annotated to this term
eSize of the background “statistical domain” used for testing
fThe actual genes that are annotated to this term from our input (one-to-one C.elegans orthologs)
gSubset of the actual genes that carry MODERATE/HIGH impact SNPs from our input