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. Author manuscript; available in PMC: 2026 Oct 17.
Published before final editing as: Neuropsychopharmacology. 2026 Sep 8:10.1038/s41386-026-02542-8. doi: 10.1038/s41386-026-02542-8

Figure 2:

Figure 2:

Effects of supplemental cocaine access (IntA: N= 12, 6M/ 6F; EA: N= 12, 6M/6F; NA: N= 11, 6M/5F) on cocaine on cocaine-vs-food choice in male and female Long Evans rats (N= 10–12, 5–6M/ 5–6F). Panels A, C, and E show percent cocaine choice during the first, second, and post-access weeks of supplemental cocaine access. Panels B, D, and F show the numbers of session total, food, and cocaine reinforcers during the first, second, and post-access weeks of supplemental cocaine access. All data points and bars represent the group means ±SEM of the last two days of each of each week for each supplemental access condition. Filled data points represent a significant (p < 0.05) difference in percent cocaine choice compared to the no access (NA) condition. * represents a significant difference in percent cocaine choice or session reinforcers earned between IntA and EA conditions. & represents a significant difference in session reinforcers compared to the NA condition.