FIG. 9.
Summary of the interactions between RTA and the PAN promoter. The PAN promoter sequence from nt −78 to −22 is shown. A TATA box is outlined. Each symbol indicates a base pair identified as being important in each analysis. Triangles are used for methylation interference assays (Fig. 4), ovals are for Rdbd binding in vitro assayed by EMSA (Fig. 6 and 8), and rectangles are for RTA transactivation in vivo (Fig. 7). Closed symbols indicate base pairs of great importance, and open symbols mark those with mild effects. The minimal length of DNA required for RTA binding is indicated under the mapped region (Fig. 5).