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. Author manuscript; available in PMC: 2026 Sep 22.
Published in final edited form as: Cancer Cell. 2026 Sep 1;44(9):1746–1760.e4. doi: 10.1016/j.ccell.2026.08.004

Table 1.

Patient Characteristics

Characteristic Genomics Cohort (n=6,789) N (%)

Sex
Male 3,689 (54.3%)
Female 3,100 (45.7%)

Age at diagnosis
<35 years 391 (5.8%)
35-50 years 1871 (27.5%)
≥50 years 4404 (64.9%)
N/A 123 (1.8%)

Primary tumor location
Right colon 2059 (30.3%)
Left colon 2577 (38.0%)
Rectum 2153 (31.7%)

Stage at diagnosis
Stages I-III 3578 (52.7%)
Stage IV 2607 (38.4%)
N/A 604 (8.9%)

Tumor molecular subtype
Microsatellite stable 5946 (87.6%)
Microsatellite instability-high 775 (11.4%)
Ultramutated (Pathogenic POLE/POLD1) 68 (1.0%)

Abbreviations: N/A: not available