Table 1:
Patient Characteristics and Demographics
| Patient Cohort | No-TBIa (34) | TBI (29) | P value and Adjusted q-value (No-TBI:TBI) |
|---|---|---|---|
|
| |||
|
Time From Injury to Blood Draw (Median Minutes) (25-75% IQR) |
44 (32-59) | 50 (38-61) | p = 0.446 q = 0.488 |
|
| |||
| Age (Median Years) (25-75% IQRb) | 33 (26-55) | 47 (31-59) | p = 0.331 q = 0.465 |
|
| |||
| Sex | 0.214 | ||
| (Male %) | 28 (82%) | 20 (69%) | |
| (Female %) | 6 (18%) | 9 (31%) | |
|
| |||
| Race | 0.757 | ||
| White | 22 (65%) | 19 (66%) | |
| Black | 10 (29%) | 7 (24%) | |
| Asian | 2 (6%) | 3 (10%) | |
|
| |||
| Ethnicity | 0.55 | ||
| Hispanic or Latino | 13 (38%) | 9 (31%) | |
| Non-Hispanic of Latino | 21 (62%) | 20 (69%) | |
|
| |||
| Injury Mechanism | <0.001 *** | ||
| Blunt | 19 (56%) | 27 (93%) | |
| Motor Vehicle Collision | 14 | 11 | |
| Fall | 4 | 7 | |
| Pedestrian Struck | 1 | 9 | |
| Penetrating | 15 (44%) | 2 (7%) | |
| Gunshot Wound | 5 | 2 | |
| Stab | 10 | 0 | |
|
| |||
| Bleed Type | - | ||
| Epidural Hematoma | 0 | 1 | |
| Subdural Hematoma | 1 | 19 | |
| Subarachnoid Hemorrhage | 1 | 24 | |
| Intraventricular Hemorrhage | 0 | 7 | |
| Intraparenchymal Hemorrhage | 0 | 15 | |
| Multi Compartment Hemorrhage | 0 | 22 | |
|
| |||
| Mortality (%) | 4 (12%) | 15 (52%) | p <0.001 *** |
|
| |||
|
Injury Severity Score (Median ISSc) (25-75% IQR) |
14 (9-21) | 26 (17-33) |
p <0.001
*** q <0.01 ## |
|
| |||
|
Glasgow Coma Score (Median GCSd) (25-75% IQR) |
15 (15-15) | 3 (3-6) |
p <0.0001
**** q <0.0001 #### |
|
| |||
|
Head Abbreviated Injury Scale (Median AISe) (25-75% IQR) |
0 (0-0.25) | 4 (3-5) |
p <0.0001
**** q <0.0001 #### |
Abbreviations:
a:
Traumatic Brain Injury (TBI),
b:
Interquartile Range (IQR),
c:
Injury Severity Score (ISS),
d:
Glasgow Coma Score (GCS),
e:
Abbreviated Injury Scale (AIS).
Significance indicated by
*
p < 0.05,
**
p < 0.01,
***
p < 0.001,
****
p < 0.0001,
and Benjamini-Hochberg FDR adjusted values
##
q < 0.01,
####
q < 0.0001.