Figure 3. Novel spatial recognition (NSR) task.
(A) At baseline, discrimination indices were significantly higher than 0 for both the HFD and Rev group, indicating a discriminatory preference toward the Novel arm. (B) At 1mo after dietary reversal, the discrimination index was significantly higher than 0 only for the Rev group, indicating a discriminatory preference toward the Novel arm. (C) At 2mo after dietary reversal the discrimination index was significantly lower than 0 only for the Rev group, indicating a discriminatory preference toward the Familiar arm. NSR performance was analyzed by one-sample T-test against 0 at each timepoint. *p <.05; **p <.01.