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Kinetics of activation during repetitive stimulation
| Channel | Nav1.2Q3 (n = 6) | Nav1.6Q3 (n = 4) | ||||
|---|---|---|---|---|---|---|
| Depolarization no. | 1 | 10 | 200 | 1 | 30 | 200 |
| Activation τfast (ms) | 0.59 ± 0.11 | 0.54 ± 0.11 | 0.54 ± 0.10 | 0.51 ± 0.14 | 0.44 ± 0.13 | 0.44 ± 0.13 |
| Activation τslow (ms) | ND* | ND* | ND* | 4.65 ± 0.83 | 3.33 ± 0.43 | 3.35 ± 0.45 |
| Percentage of τfast (%) | ND* | ND* | ND* | 84 ± 5 | 88 ± 2 | 88 ± 2 |
Not determined because the activation of Nav1.2Q3 was best fit with a single exponential equation.
