. Author manuscript; available in PMC: 2026 Feb 4.

Published in final edited form as: Am J Psychiatry. 2013 Nov;170(11):1263–1274. doi: 10.1176/appi.ajp.2013.12101339

TABLE 4. Family History of Psychiatric Disorders in Probands With Schizophrenia, Schizoaffective Disorder, or Psychotic Bipolar I Disorder.

Relative’s Diagnosis	Probands With Schizophrenia (N=397)				Probands With Schizoaffective Disorder (N=224)				Probands With Bipolar Disorder (N=312)
	First-Degree Relatives		Second-Degree Relatives		First-Degree Relatives		Second-Degree Relatives		First-Degree Relatives		Second-Degree Relatives
	N	%	N	%	N	%	N	%	N	%	N	%
Schizophrenia or schizoaffective disorder	70	17.6	89	22.4	46	20.5	62	27.7	42	13.5	45	14.4
Bipolar disorder	61	15.4	48	12.1	81	36.2	75	33.5	139	44.6	95	30.5
Depressive disorder	112	28.2	79	19.9	121	54.0	83	37.1	172	55.1	119	38.1
Suicide or suicide attempt	30	7.6	46	11.6	24	10.7	34	15.2	53	17.0	48	15.4
Alcoholism	129	32.5	147	37.0	100	44.6	110	49.1	131	42.0	148	47.4
Illicit substance use	81	20.4	73	18.5	81	36.2	67	29.9	105	33.7	66	21.2
Other psychiatric disorder	73	18.4	79	19.9	46	20.5	59	26.3	99	31.7	103	33.0