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Histology of S. aureus infection in the murine lung. Control, BALBc/ByJ mouse inoculated with PBS. RN6390, wild type (note edema, PMN infiltration, and loss of air spaces). ALC135, agr sarA mutant. RN6911, agr mutant. ALC136, sarA mutant (PMN infiltration and edema are similar to those associated with infection due to the wild-type strain). Magnification, ×250.
