FIG. 4.
Coinoculation of E. coli CFT073 fim pap and CFT073-OFF in the murine model of ascending UTI. E. coli CFT073 fim pap and CFT073-OFF were inoculated together into the murine urinary tract. At the indicated times postinoculation, mice (n = 8) were sacrificed and the level of colonization was determined for each strain in the urine (A), in the bladder (B), and in the kidneys (C). Individual counts of strain CFT073-OFF are represented by squares (□), and individual counts of strain CFT073 fim pap are represented by circles (○). Bars, representing the median counts, are connected by a solid line in CFT073-OFF, and a dotted line in CFT073 fim pap.