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. 2002 Jul;46(7):2238–2243. doi: 10.1128/AAC.46.7.2238-2243.2002

TABLE 4.

Most frequently occurring adverse events in patients treated with ACV cream or vehicle cream

Adverse event No. in study 1 (%)
No. in study 2 (%)
Acyclovir (n = 334) Vehicle (n = 352) Acyclovir (n = 348) Vehicle (n = 351)
Headache 3 (<1) 9 (3) 5 (1) 6 (2)
Flakiness of skin 0 (0) 0 (0) 1 (<1) 6 (2)
Desquamation 2 (<1) 1 (<1) 1 (<1) 4 (1)