TABLE 2.
Baseline patient characteristics stratified by passive cardiac index (PasCI)
| Characteristic | PasCI ≤0.778 (n = 266) | PasCI >0.778 (n = 133) | P value |
|---|---|---|---|
|
| |||
| Age (y) | 64.0 (56.0–70.0) | 61.0 (52.0–67.0) | .026 |
| Male sex | 216 (81.2) | 101 (75.9) | .220 |
| BMI | 28.0 (24.0–32.0) | 30.0 (26.0–34.0) | .026 |
| NYHA functional class | 4.0 (3.0–4.0) | 4.0 (3.0–4.0) | .231 |
| Diabetes | 68 (25.6) | 45 (33.8) | .084 |
| Coronary artery disease | 163 (61.3) | 65 (48.9) | .018 |
| Pulmonary hypertension | 174 (65.4) | 76 (57.1) | .107 |
| Creatinine (mg/dL) | 1.3 (1.0–1.6) | 1.4 (1.1–1.8) | .001 |
| Ischemic cardiomyopathy | 137 (51.5) | 52 (39.1) | .019 |
| Total bilirubin (mg/dL) | 1.0 (0.7–1.5) | 1.2 (0.8–1.9) | .016 |
| Albumin (g/dL) | 3.9 (3.6–4.2) | 3.7 (3.3–4.0) | .004 |
| LVEF (%) | 18.0 (14.0–22.0) | 19.0 (15.0–23.0) | .051 |
| Moderate/severe RV dysfunction | 136 (52.1) | 80 (62.5) | .053 |
| Moderate/severe MR | 150 (56.6) | 57 (43.2) | .013 |
| Moderate/severe TR | 124 (47.3) | 85 (65.9) | <.001 |
| Right atrial pressure (mm Hg) | 11.0 (7.0–14.0) | 19.0 (15.0–23.0) | <.001 |
| Mean pulmonary artery pressure (mm Hg) | 35.5 (30.0–40.0) | 35.0 (30.0–40.0) | .418 |
| PCWP (mm Hg) | 22.0 (17.0–27.0) | 24.5 (20.2–28.0) | .004 |
| Cardiac output (L/min) | 3.4 (2.7–4.2) | 3.9 (3.4–4.7) | <.001 |
| Cardiac index (L/min/m2) | 1.7 (1.4–2.0) | 2.0 (1.7–2.3) | <.001 |
| Renal replacement therapy | 6 (2.3) | 6 (4.5) | .214 |
| IABP | 109 (41.0) | 71 (53.4) | .019 |
| Impella device* | 6 (2.3) | 2 (1.5) | .613 |
| ECMO | 4 (1.5) | 3 (2.3) | .312 |
| Inotropes | 184 (69.7) | 85 (63.9) | .244 |
Values are presented as n (%) or median (interquartile range). BMI, Body mass index; NYHA, New York Heart Association; LVEF, left ventricular ejection fraction; RV, right ventricle; MR, mitral regurgitation; TR, tricuspid regurgitation; PCWP, pulmonary capillary wedge pressure; IABP, intra-aortic balloon pump; ECMO, extracorporeal membrane oxygenation.
*
Abiomed.