FIG. 7.

Kinetics of the virus-specific and total serum Ig response in mice infected with MHV-68. Each point shows the mean and standard deviation of results from three to six individual mouse sera pooled from four experiments. The neutralizing antibody titer (B) was determined by plaque inhibition (see Materials and Methods), whereas other antibody titers (A and C) were determined by ELISA. All measurements were made relative to a standard pool of immune sera and are expressed in arbitrary units.