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. 2002 Mar 19;99(7):4185–4190. doi: 10.1073/pnas.022039799

Table 1.

Amino acid compositions of Cre libraries and evolved variants

M44 V48 T87 Q90 H91 I174 T258 R259 E262 E266 Y283
C1 library X* X X X X I T R E E X
C1(+) #1 G V T S A I T R E E Y
C2 library M V T Q H X X X X X Y
C2(+) #1 M V T Q H L N S G G Y
C2(±) #4 M V T Q H A L S H G Y
*

X indicates a random amino acid residue; mutations relative to wild-type Cre are shown in bold.