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. 2025 Jul 29;11(4):e200283. doi: 10.1212/NXG.0000000000200283

Table 2.

Mean Annual FF Progression Rate per Muscle and Predicted Mean Value of FF at 40 Years Old

Segment
Muscle Mean annual FF progression rate (%) FF value at 40 yo according to the model (%)
Thigh 1.17 51.7
Anterior compartment
 VM 1.14 48.8
 VL 1.18 49.3
 VI 1.18 51.9
Posterior compartment
 BF 1.15 59.0
 SM 1.14 67.0
 ST 1.20 56.6
Medial compartment
 AM 1.19 57.7
 Sar 1.05 32.1
 Gra 0.99 27.4
 Lower leg 1.04 48.2
Anterior compartment
 ED 1.11 30.3
 TA 1.11 37.4
Posterior compartment
 TP 1.11 34.1
 GL 1.06 52.3
 Sol 1.03 57.5
 GM 0.96 58.1
Lateral compartment
 Per 1.04 53.1

Abbreviations: AM = adductor magnus; BF = biceps femoris; ED = extensor digitorum muscles; FF = fat fraction; GM = gastrocnemius medialis; GL = gastrocnemius lateralis; Gra = gracilis; Per = peroneals; Sar = sartorius; SM = semimembranosus; Sol = soleus; ST = semitendinosus; TA = tibialis anterior; TP = tibialis posterior; VI = vastus intermedius; VL = vastus lateralis; VM = vastus medialis; yo = years old.