Table 2.
In-hospital complications and outcomes of AMI cohort across liver indices.
| Overall for FIB-4 and APRIc (N = 3287) |
FIB-4 < 1.3 (N = 455) |
1.3 ≤ FIB-4 < 3.25 (N = 1027) |
FIB-4 ≥ 3.25 (N = 1805) |
p-value | APRI ≤ 0.3 (N = 685) |
0.3 < APRI < 1.5 (N = 1369) |
APRI ≥ 1.5 (N = 1233) |
p-value | Overall for NFSb, c (N = 2143) |
NFS < -1.455 (N = 161) |
-1.455 ≤ NFS ≤ 0.676 (N = 684) |
NFS > 0.676 (N = 1298) |
p-value | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| In-hospital complications | ||||||||||||||
| Cardiac arrest | 201 (6.1) | 9 (2.0) | 27 (2.6) | 165 (9.1) | p < 0.001 | 9 (1.3) | 27 (2.0) | 165 (13.4) | p < 0.001 | 144 (6.7) | 6 (3.7) | 48 (7.0) | 90 (6.9) | p = 0.288 |
| Heart failure | 847 (25.8) | 89 (19.6) | 251 (24.4) | 507 (28.1) | p < 0.001 | 154 (22.5) | 345 (25.2) | 348 (28.2) | p = 0.025 | 683 (31.9) | 23 (14.3) | 203 (29.7) | 457 (35.2) | p < 0.001 |
| Cardiogenic shock | 455 (13.8) | 26 (5.7) | 67 (6.5) | 362 (20.1) | p < 0.001 | 22 (3.2) | 89 (6.5) | 344 (27.9) | p < 0.001 | 341 (15.9) | 5 (3.1) | 89 (13.0) | 247 (19.0) | p < 0.001 |
| Stroke | 126 (3.8) | 14 (3.1) | 35 (3.4) | 77 (4.3) | p = 0.349 | 20 (2.9) | 38 (2.8) | 68 (5.5) | p < 0.001 | 105 (4.9) | 6 (3.7) | 36 (5.3) | 63 (4.9) | p = 0.677 |
| Outcomes | ||||||||||||||
| 30-day all-cause mortality | 420 (12.8) | 25 (5.5) | 69 (6.7) | 326 (18.1) | p < 0.001 | 38 (5.5) | 101 (7.4) | 281 (22.8) | p < 0.001 | 316 (14.7) | 7 (4.3) | 63 (9.2) | 246 (19.0) | p < 0.001 |
| 30-day cardiac mortality | 369 (11.2) | 21 (4.6) | 57 (5.6) | 291 (16.1) | p < 0.001 | 31 (4.5) | 79 (5.8) | 259 (21.0) | p < 0.001 | 273 (12.7) | 5 (3.1) | 55 (8.0) | 213 (16.4) | p < 0.001 |
| Long-term all-cause mortality | 1065 (32.4) | 101 (22.2) | 298 (29.0) | 666 (36.9) | p < 0.001 | 208 (30.4) | 418 (30.5) | 439 (35.6) | p = 0.010 | 831 (38.8) | 24 (14.9) | 235 (34.4) | 572 (44.1) | p < 0.001 |
aCategorical variables are presented as n (%). p < 0.050 is taken as statistical significance (in bold).
bAbbreviations: AMI, acute myocardial infarction; APRI, aspartate aminotransferase (AST) to Platelet Ratio Index; FIB-4, Fibrosis-4 index; NFS, Non-alcoholic Fatty Liver Disease Fibrosis Score; T2DM, type 2 diabetes mellitus.