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| NaV channel | Threshold (mV) | Peak dV/dt (V/s) |
|---|---|---|
| Wildtype, no drug (n = 12) | –43.1 ± 0.4 | 549.1 ± 8.8 |
| Wildtype + GNE-4076 (n = 12) | –41.7 ± 0.7 | 541.0 ± 12.5 |
| Scn8a/2aSR/SR + GNE-4076 (n = 12) | –43.7 ± 0.4 | 561.3 ± 14.5 |
| Scn2aSR/SR + GNE-4076 (n = 12) | –40.7 ± 0.4 | 500.7 ± 12.5 |
| Scn8aSR/SR + GNE-4076 (n = 11) | –43.3 ± 0.5 | 542.9 ± 11.6 |
