Figure 2.
Loss of function of Nkx3.1 and Pten cooperate in prostate cancer progression. A graphical representation of the percentage of mice lacking HGPIN/early carcinoma lesions in the dorsolateral prostate at the indicated ages is shown. Incidence corresponds to the occurrence of HGPIN/early carcinoma lesions, which is defined by using the histopathological and morphological criteria described in the text. The percentage incidence-free was calculated by dividing the number of unaffected mice by the total number of mice analyzed for each age group.