Table 3.
Univariate Cox proportional hazards analysis for survival of HCC patients
| Hazard ratio | 95% CI | P-value | |
|---|---|---|---|
| Age (≥60/<60) | 1.50 | 0.71–3.19 | 0.293 |
| Gender (man/woman) | 1.04 | 0.42–2.58 | 0.928 |
| HBV (+/−) | 1.11 | 0.41–3.02 | 0.834 |
| HCV (+/−) | 0.77 | 0.30–2.00 | 0.592 |
| Cirrhosis (+/−) | 1.28 | 0.56–2.96 | 0.562 |
| Histologic grade (PD/WD, MD) | 1.95 | 0.90–4.22 | 0.091 |
| Tumor size (cm) | 1.16 | 1.05–1.28 | 0.005 |
| Stage (III–IV/I–II) | 5.96 | 2.71–13.11 | <0.001 |
| C/EBPα (I/II–III)a | 4.94 | 1.79–13.68 | 0.002 |
PD poorly differentiated, WD well differentiated, MD moderately differentiated
aI C/EBPα score (tumor − nontumor) (T − N) = −2; II T − N = −1; III T − N ≥ 0