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. 1983 Aug;341:279–307. doi: 10.1113/jphysiol.1983.sp014806

Spatio-temporal interactions in cat retinal ganglion cells showing linear spatial summation.

C Enroth-Cugell, J G Robson, D E Schweitzer-Tong, A B Watson
PMCID: PMC1195335  PMID: 6620181

Abstract

The spatio-temporal characteristics of cat retinal ganglion cells showing linear summation have been studied by measuring both magnitude and phase of the responses of these cells to drifting or sinusoidally contrast-modulated sinusoidal grating patterns. It has been demonstrated not only that X cells behave approximately linearly when responding with amplitudes of less than about 10 impulses/sec to stimuli of low contrast but also that cells of another type with larger receptive field centres (Q cells) behave approximately linearly under the same conditions. These Q cells appear to form a homogeneous group which is probably a subset of the tonic W cells (Stone & Fukuda, 1974) or sluggish centre-surround cells (Cleland & Levick, 1974). The over-all spatio-temporal frequency characteristics of cells showing linear spatial summation are not separable in space and time. The form of the spatial frequency responsivity function of these cells depends upon the temporal frequency at which it is measured while the temporal phase of their resonse measured at any constant temporal frequency depends upon the spatial frequency of the stimulus. The behaviour of X and Q cells is quite well explained by an extension of the model in which signals from centre and surround mechanisms with radially Gaussian weighting functions are summed to provide the drive to the retinal ganglion cell. While the general form of the temporal frequency response characteristics of these ganglion cells are probably provided by the characteristics of elements common to the centre and surround pathways, the spatio-temporal interactions can be explained by assuming that the surround signal is delayed relative to the centre signal by a few milliseconds.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burbeck C. A., Kelly D. H. Contrast gain measurements and the transient/sustained. J Opt Soc Am. 1981 Nov;71(11):1335–1342. doi: 10.1364/josa.71.001335. [DOI] [PubMed] [Google Scholar]
  2. Burbeck C. A., Kelly D. H. Spatiotemporal characteristics of visual mechanisms: excitatory-inhibitory model. J Opt Soc Am. 1980 Sep;70(9):1121–1126. doi: 10.1364/josa.70.001121. [DOI] [PubMed] [Google Scholar]
  3. Cleland B. G., Levick W. R. Brisk and sluggish concentrically organized ganglion cells in the cat's retina. J Physiol. 1974 Jul;240(2):421–456. doi: 10.1113/jphysiol.1974.sp010617. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Derrington A. M., Lennie P. The influence of temporal frequency and adaptation level on receptive field organization of retinal ganglion cells in cat. J Physiol. 1982 Dec;333:343–366. doi: 10.1113/jphysiol.1982.sp014457. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Enroth-Cugell C., Lennie P. The control of retinal ganglion cell discharge by receptive field surrounds. J Physiol. 1975 Jun;247(3):551–578. doi: 10.1113/jphysiol.1975.sp010947. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Enroth-Cugell C., Robson J. G. The contrast sensitivity of retinal ganglion cells of the cat. J Physiol. 1966 Dec;187(3):517–552. doi: 10.1113/jphysiol.1966.sp008107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Foerster M. H., van de Grind W. A., Grüsser O. J. Frequency transfer properties of three distinct types of cat horizontal cells. Exp Brain Res. 1977 Sep 28;29(3-4):347–366. doi: 10.1007/BF00236175. [DOI] [PubMed] [Google Scholar]
  8. Foerster M. H., van de Grind W. A., Grüsser O. J. The response of cat horizontal cells to flicker stimuli of different area, intensity and frequency. Exp Brain Res. 1977 Sep 28;29(3-4):367–385. doi: 10.1007/BF00236176. [DOI] [PubMed] [Google Scholar]
  9. Gestri G., Maffei L., Petracchi D. Spatial and temporal organization in retinal units. Kybernetik. 1966 Nov;3(4):196–202. doi: 10.1007/BF00290257. [DOI] [PubMed] [Google Scholar]
  10. Hochstein S., Shapley R. M. Quantitative analysis of retinal ganglion cell classifications. J Physiol. 1976 Nov;262(2):237–264. doi: 10.1113/jphysiol.1976.sp011594. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kirby A. W., Schweitzer-Tong D. E. GABA-antagonists and spatial summation in Y-type cat retinal ganglion cells. J Physiol. 1981 Mar;312:335–344. doi: 10.1113/jphysiol.1981.sp013631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Lee B. B., Elepfandt A., Virsu V. Phase of responses to moving sinusoidal gratings in cells of cat retina and lateral geniculate nucleus. J Neurophysiol. 1981 May;45(5):807–817. doi: 10.1152/jn.1981.45.5.807. [DOI] [PubMed] [Google Scholar]
  13. Levick W. R., Thibos L. N. Analysis of orientation bias in cat retina. J Physiol. 1982 Aug;329:243–261. doi: 10.1113/jphysiol.1982.sp014301. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Linsenmeier R. A., Frishman L. J., Jakiela H. G., Enroth-Cugell C. Receptive field properties of x and y cells in the cat retina derived from contrast sensitivity measurements. Vision Res. 1982;22(9):1173–1183. doi: 10.1016/0042-6989(82)90082-7. [DOI] [PubMed] [Google Scholar]
  15. Mastronarde D. N. Correlated firing of cat retinal ganglion cells. I. Spontaneously active inputs to X- and Y-cells. J Neurophysiol. 1983 Feb;49(2):303–324. doi: 10.1152/jn.1983.49.2.303. [DOI] [PubMed] [Google Scholar]
  16. Movshon J. A., Thompson I. D., Tolhurst D. J. Spatial and temporal contrast sensitivity of neurones in areas 17 and 18 of the cat's visual cortex. J Physiol. 1978 Oct;283:101–120. doi: 10.1113/jphysiol.1978.sp012490. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Pettigrew J. D., Cooper M. L., Blasdel G. G. Improved use of tapetal reflection for eye-position monitoring. Invest Ophthalmol Vis Sci. 1979 May;18(5):490–495. [PubMed] [Google Scholar]
  18. Rodieck R. W. Quantitative analysis of cat retinal ganglion cell response to visual stimuli. Vision Res. 1965 Dec;5(11):583–601. doi: 10.1016/0042-6989(65)90033-7. [DOI] [PubMed] [Google Scholar]
  19. Rodieck R. W., Stone J. Analysis of receptive fields of cat retinal ganglion cells. J Neurophysiol. 1965 Sep;28(5):832–849. doi: 10.1152/jn.1965.28.5.833. [DOI] [PubMed] [Google Scholar]
  20. Shapley R. M., Victor J. D. The effect of contrast on the transfer properties of cat retinal ganglion cells. J Physiol. 1978 Dec;285:275–298. doi: 10.1113/jphysiol.1978.sp012571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Stone J., Fukuda Y. Properties of cat retinal ganglion cells: a comparison of W-cells with X- and Y-cells. J Neurophysiol. 1974 Jul;37(4):722–748. doi: 10.1152/jn.1974.37.4.722. [DOI] [PubMed] [Google Scholar]
  22. Victor J. D., Shapley R. M. Receptive field mechanisms of cat X and Y retinal ganglion cells. J Gen Physiol. 1979 Aug;74(2):275–298. doi: 10.1085/jgp.74.2.275. [DOI] [PMC free article] [PubMed] [Google Scholar]

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