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The distribution of function within the phyletic groups
| Phyletic groups/functional groups | Total functionally annotated proteins (%) | Enzymes, % | Transporters, % | Transcription factors, % | Signal transduction, % |
| Universal | 833 (31%) | 82 | 15 | 2 | 1 |
| Eukaryote-specific | 823 (31%) | 60 | 18 | 12 | 10 |
| Metazoan-specific | 656 (24%) | 26 | 7 | 23 | 44 |
| Mammalian-specific | 372 (14%) | 13 | 17 | 6 | 64 |
| All | 2,684 | 52 | 14 | 11 | 23 |
