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Embryonal development of mutant and P0-Cre/Apc580S/+mice. Appearance of P0-Cre/Apc580S/+ embryos (A–C) and mutants (D–F) at various developmental stages indicated below the panels. Embryos at 9.5 and 11.5 dpc were stained with X-gal. In 11.5 dpc P0-Cre/Apc580S/+ embryos, frontonasal mass, trigeminal ganglia, branchial arches, and DRG were positive for LacZ. Fnm, frontonasal mass; Tg, trigeminal ganglia; Ba, branchial arch; Ot, otocyst; DRG, dorsal root ganglia. (Scale bars, 0.5 mm.)
