Table 1.
Clinical characteristics of patients
| Long PFS (n = 16) | Short PFS (n = 13) | p-value* | |
|---|---|---|---|
| Age [years (mean)] | 57.5 ± 7.9 | 60 ± 6.4 | 0.091 |
| Gender | |||
| Male [52% (n = 15)] | Male [44% (n = 7)] | Male [62% (n = 8)] | 0.34 |
| Female [48% (n = 14)] | Female [56% (n = 9)] | Female [38% (n = 5)] | |
| Histology | |||
| ADC [65% (n = 19)] | ADC [63% (n = 10)] | ADC [70% (n = 9) | 0.895 |
| SCC [25% (n = 7)] | SCC [25% (n = 4)] | SCC [23% (n = 3)] | |
| NSCLC-NOS [10% (n = 3)] | NSCLC-NOS [12%(n = 2)] | NSCLC-NOS [7% (n = 1)] | |
| Stage | |||
| IIIb [24% (n = 7)] | IIIb [19% (n = 3)] | IIIb [31% (n = 4)] | 0.451 |
| IV [76% (n = 22)] | IV [81% (n = 13)] | IV [69% (n = 9)] | |
| PFS [months, (median)] | 15.8 ± 9.4 months | 3.2 ± 1.7 months | < 0.001 |
| Chemotherapy | |||
| Treated [31% (n = 9)] | Treated [13% (n = 2)] | Treated [54% (n = 7)] | 0.039* |
| Naive [69% (n = 17)] | Naive [87% (n = 11)] | Naive [46% (n = 6)] | |
| PD-L1 TPS | |||
| > 50% [55% (n = 16)] | > 50% [75% (n = 12)] | > 50% [31% (n = 4)] | 0.023* |
| ≤ 50% [34% (n = 10)] | ≤ 50% [19% (n = 3)] | ≤ 50% [54% (n = 7)] | |
| N/A [11% (n = 3)] | N/A [6% (n = 1)] | N/A [15% (n = 2)] | |
| Smoking [pack-years (mean)] | 40.1 ± 8.5 | 37.3 ± 10.6 | 0.26 |
| COPD comorbidity | |||
| Yes [31% (n = 9)] | Yes [38% (n = 6)] | Yes [23% (n = 3)] | 0.483 |
| No [66% (n = 19)] | No [62% (n = 10)] | No [70% (n = 9)] | |
| N/A [3% (n = 1)] | N/A [0% (n = 0)] | N/A [7% (n = 1)] | |
| BMI | |||
| > 30 kg/m2 [21% (n = 6)] | > 30 kg/m2 [12% (n = 2)] | > 30 kg/m2 [31% (n = 4)] | 0.151 |
| ≤ 30 kg/m2 [62% (n = 18)] | ≤ 30 kg/m2 [75% (n = 12)] | ≤ 30 kg/m2 [46% (n = 6)] | |
| N/A [17% (n = 5)] | N/A [13% (n = 2)] | N/A [23% (n = 3)] |
*Chi squared test