FIG. 6.
The activity of the lytic vGCR promoter in the presence of TPA in different cell lines. NIH 3T3 (A), BJAB (B), and BCBL-1 (C) cells were transfected with the indicated plasmids containing the vGCR promoter in either the sense (pDD163) or antisense (pDD168) orientation with respect to the reporter gene and stimulated with TPA (20 ng/ml). Bars represent the mean fold induction after 72 h normalized for transfection efficiency using a cotransfected β-galactoside reporter in triplicate (error bars, standard deviations). In panel C the difference in mean between pDD163 and pDD168 is significant (P ≤ 0.05).