Figure 1.
Established clones showing peptide‐specific cytotoxicity. (a) The cytotoxic T lymphocyte (CTL) clone raised against TTK‐567 had peptide‐specific cytotoxicity. It showed high cytotoxic activity against target cells (A24LCL) pulsed with TTK‐567 (—▪—), whereas it did not show significant cytotoxic activity against the same target cells (A24LCL) pulsed with no peptides (—□—). (b) The CTL clone raised against LY6K‐177 had peptide‐specific cytotoxicity. The CTL clone showed high cytotoxic activity against target cells (A24LCL) pulsed with LY6K‐177 (—▪—), whereas it did not show significant cytotoxic activity against the same target cells (A24LCL) pulsed with no peptides (—□—). (c) The CTL clone raised against IMP‐3‐508 had peptide‐specific cytotoxicity. The CTL clone showed high cytotoxic activity against target cells (A24LCL) pulsed with IMP‐3‐508 (—▪—), whereas it did not show significant cytotoxic activity against the same target cells (A24LCL) pulsed with no peptides (—□—). This demonstrates that all three CTL clones had peptide‐specific cytotoxicity.