TABLE 4.
Infected neuronal populations of the TG: outcomes analysisa
| Antiserum | HSV Ag+
|
LAT+
|
HSVAg+/LAT+ | ||
|---|---|---|---|---|---|
| % | n | % | n1 | ||
| SSEA3 | 28 | 976 | 81 | 973 | 1:1 |
| TrkA | 21 | 732 | 71 | 853 | 1:1.2 |
| A5 | 7 | 244 | 68 | 817 | 1:3.3 |
| KH10 | 16 | 567 | 2 | 24 | 23:1 |
| RT97b | 49 | 1,707 | 34 | 408 | 4.2:1 |
| b-NOS | 2 | 70 | 3 | 36 | 1.9:1 |
| CGRP | 31 | 1,080 | 51 | 613 | 1.8:1 |
| SP | 12 | 418 | 20 | 240 | 1.7:1 |
| Total | 3,483 | 1,201 | 2.9:1 | ||
n, number of HSV antigen-positive (Ag+) neurons at 3 days p.i.; n1, number of LAT-positive neurons at 21 days p.i.
Since we have no data on the percentage of neurons latently infected with KOS that coexpress RT97, for the purposes of the analysis presented here we used data from mice infected with KOS/62.