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. 2024 May 23;15(1):2352203. doi: 10.1080/19491034.2024.2352203

Figure 4.

Figure 4.

Schematic diagram of NE-component accumulation at or localization to the core region and the NE plaque. (Top) during mitosis, LA/C and LEM-domain proteins are recruited to the core region with BAF, followed by the accumulation of CHMPs to form a macromolecular O-ring. (Bottom) Phosphorylated BAF (p-BAF) recruits LC from the nucleoplasm to form the NE plaque on the surface of chromatin exposed to the cytoplasm at the opening area of a rupture site.