Table 4.
Comparison of TAA-specific CTL in blood and tumor
| Patient | Circulating TAA-specific CTL preceding vaccination | TAA-specific TIL |
|---|---|---|
| 1 | MART26–35 | gp100154–162 |
| 2 | All negative | MART26–35 |
| 3 | All negative | Tyrosinase368–376 |
| 4 | All negative | MART26–35 + gp100154–162 |
| 5 | All negative | MART26–35 + gp100154–162 |
| 6 | All negative | gp100154–162 |
| 7 | All negative | All negative |
| 8 | All negative | All negative |
The table shows results of tetramer analyses in patients of which both blood and tumor tissue were available. Preceding vaccination therapy, in no patient CTL were found for the same TAA in both blood and tumor tissue
TAA-specific CTL tumor-associated-antigen-specific cytotoxic T lymphocytes