Table 3.
HLA-tetramer analyses of tumor-infiltrating lymphocytes (TIL)
| Patient | TAA-specific TIL | TIL as a percentage of live cells in melanoma tissue | TAA-specific TIL as a percentage of all TIL in melanoma tissue |
|---|---|---|---|
| 1 | gp100280–288 | 10.7 | 1.5 |
| 2 | MART26–35 | 10.2 | 6.6 |
| 3 | Tyrosinase368–376 | 19.0 | 0.2 |
| 4 | MART26–35 + gp100154–162 | 13.9 | 1.7, 0.8 |
| 5 | MART26–35 + gp100154–162 | 18.7 | 0.3, 4.1 |
| 6 | gp100154–162 | 13.3 | 3.5 |
| 7 | All negative | 7.5 | – |
| 8 | All negative | 5.4 | – |
| 18 | MART26–35 + gp100154–162 + gp100280–288 | 14.2 | 1.4, 2.8, 3.7 |
| 19 | MART26–35 | 21.6 | 4.2 |
| 20 | MART26–35 | 9.9 | 0.9 |
| 21 | gp100154–162 + gp100280–288 | 16.5 | 0.8, 0.9 |
| 22 | gp100280–288 | 8.2 | 1.6 |
| 23 | gp100280–288 | 11.6 | 1.7 |
| 24 | All negative | 7.8 | – |
| 25 | All negative | 27.9 | – |
The third column shows the percentage of TIL compared to the total number of cells present inside the melanoma tissue and the fourth column shows the percentage of tumor-associated antigen-specific TIL (TAA-specific TIL) compared to the total number of TIL