Fig. 2.
Caspase-dependent apoptosis of poly(I:C)-treated LNCaP cells. a LNCaP cells were cultured with (closed symbols) or without (open symbols) 10 μg/ml poly(I:C) for 48 h, and flow cytometry analysis was performed. Numbers represent the percentage of cells in each subset. The histogram represents a summary of results from three flow cytometry experiments. *P < 0.05 indicates statistical significance. AV, Annexin V. pIC, poly(I:C). b Protein expression was assessed in cancer cell lines cultured with or without 10 μg/ml poly(I:C) for 48 h. c LNCaP cells were cultured with or without 10 μg/ml poly(I:C) for 48 h in the presence of DMSO or 20 μM z-VAD, and flow cytometry analysis was performed. Numbers represent the percentage of cells in each subset. The histogram represents a summary of results from three independent data. *P < 0.05 indicates statistical significance