Figure 5. IMR preserves cortical bone.

Average values at the conclusion of the experiment (eight weeks) are shown for (A,G) cortical thickness (Ct. Th), (B,H) endosteal radius, (C,I) periosteal radius, (D,J) endosteal circumference, (E,K)periosteal circumference, and (F,L) polar moment of inertia (pMOI). Values were determined by micro-CT analyses of tibiae (panels (A)–(F)) and femurs (panels (G)–(L)), respectively. Bars denote SEM. Statistically significant differences are either indicated (*, p < 0.05; **, p < 0.01; ****, p < 0.0001) or absent (ns). N = 8 for all groups.