FIG. 6.
Lung histopathology. Mice were primed with VSC8 (A), VSC8 plus G (B), vvWT G (C), vvM48 (D), vvM48I (E), or vvM48I plus G (F) and challenged as for Fig. 3. Eight days following challenge, lung histopathology was evaluated by staining formalin-fixed lung sections with hematoxylin and eosin (original magnification, ×25). Day 8 lungs were examined and graded for severity and composition of alveolar inflammation on a semiquantitative scale (G). No statistical difference was found among any group except the VSC8-plus-G group, in which inflammation was significantly higher than in any other group (P < 0.03, Student’s t test, n = 5).