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Summary of the functional characteristics of substituted envelopesa
| Envelope SU | SU-TM cleavage | Shedding | Surface expression | Virion incorporation | Receptor binding | Infection interference | Infection of target cells |
|---|---|---|---|---|---|---|---|
| A | + | − | + | + | + | + | + |
| AΔ1 | +, ts | + | + | + | − | − | − |
| AΔ2 | − | − | − | − | − | − | − |
| AΔ3 | +, ts | − | + | + | + | + | + |
| AΔ4 | +, ts | − | + | + | − | − | + |
| AΔ5 | + | − | + | + | + | + | + |
Characteristics are listed as present (+) or absent (−) for each protein.
