Figure 3.
Cytokine concentrations in synovial and serum specimens of RA patients. Concentrations of 5 cytokines, including IL-18, IL-10, IL-12, TNF-α, and IFN-γ, were measured by ELISA in the same paired SF specimens and paired sera of RA patients as well as in control sera as described in the Figure 2 legend. Single asterisks indicate statistically significant differences between RA specimens (RA-SF or RA-sera) and control sera (P < 0.01) while double asterisks represent significant differences between RA-SF and RA-sera or control sera (P < 0.01).