. 1998 Apr;42(4):879–884. doi: 10.1128/aac.42.4.879

TABLE 5.

Nucleotide substitutions determined by sequencing of the previously oligotyped IRT-encoding genes and the bla_TEM gene of strain AP7 compared with the sequence of bla_TEM-1A

Nucleotide position^a	Nucleotide change (amino acid)^b
Nucleotide position^a	bla_TEM-1A	bla_TEM-33	bla_TEM-34	bla_TEM-36	bla_TEM-37	bla_TEM-38	bla_TEM-39	AP7
32	C					T
162	G		T	T	T		T
175	A	G				G		G
226	C					T
346	A		G	G	G		G
436	C	T	T	T	T	T	T
604	G	T
682	T		C	C	C
925	G			A
929	C (Arg-244)							A (Ser)
980	G (Val-261)							A (Ile)

Nucleotide numbering is according to Sutcliffe (34).

The amino acid is indicated when a point mutation leads to an amino acid substitution compared with the sequence of TEM-1 (pBR322). The numbering is according to Ambler et al. (2).